In addition, researchers also found that recent shift work might be most relevant for coronary heart disease risk and that longer time since stopping shift work was associated with decreased coronary heart disease risk, a new finding that researchers note warrants replication. Over the 24-year period, more than 10,000 newly developed cases of coronary heart disease occurred. Questionnaires also collected data on known risk factors of coronary heart disease every two to four years throughout the study period. In the case of a self-reported heart attack, or death, information was confirmed by medical records and death certificates to ensure that the event was related to coronary heart disease.
These women also reported on their coronary health, indicating whether they had an angiogram that confirmed coronary heart disease-related chest pain, a heart attack or cardiovascular procedures such as angioplasty, coronary artery bypass graft surgery or stents. Researchers examined the association between rotating night shift work and coronary heart disease over a period of 24 years. About 189,000 women in the Nurses’ Health Study I and II who reported their lifetime exposure to rotating night shift work (defined as three or more night shifts per month, in addition to day and evening shifts) in 19 were included in the analysis. “Even though the absolute risk is small and the contribution of shift work to coronary heart disease is modest, it is important to note that this is a modifiable risk factor, and changing shift schedules may have an impact on the prevention of coronary heart disease.” These are all critical factors when thinking how to prevent coronary heart disease. However, even after controlling for these risk factors, we still saw an increased risk of coronary heart disease associated with rotating shift work,” said lead author Celine Vetter, an HMS instructor in medicine and a chronobiologist at Brigham and Women’s. “There are a number of known risk factors for coronary heart disease, such as smoking, poor diet, lack of physical activity and elevated body mass index. In a new study from Brigham and Women’s Hospital and Harvard Medical School published in the April 26 issue of JAMA, researchers found that women who work more than 10 years of rotating night shift work had a 15 to 18 percent increased risk of developing coronary heart disease, the most common type of heart disease, as compared with women who did not work rotating night shifts. Heart disease is the leading cause of death in the United States. Resources for those affected by War in Ukraine.Celebrating 50 Years of Diversity and Inclusion.Research Departments, Centers, Initiatives and more.
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